Abstract

Biomedical engineers prefer decision forests over traditional decision trees to design state-of-the-art Parkinson’s Detection Systems (PDS) on massive acoustic signal data. However, the challenges that the researchers are facing with decision forests is identifying the minimum number of decision trees required to achieve maximum detection accuracy with the lowest error rate. This article examines two recent decision forest algorithms Systematically Developed Forest (SysFor), and Decision Forest by Penalizing Attributes (ForestPA) along with the popular Random Forest to design three distinct Parkinson’s detection schemes with optimum number of decision trees. The proposed approach undertakes minimum number of decision trees to achieve maximum detection accuracy. The training and testing samples and the density of trees in the forest are kept dynamic and incremental to achieve the decision forests with maximum capability for detecting Parkinson’s Disease (PD). The incremental tree densities with dynamic training and testing of decision forests proved to be a better approach for detection of PD. The proposed approaches are examined along with other state-of-the-art classifiers including the modern deep learning techniques to observe the detection capability. The article also provides a guideline to generate ideal training and testing split of two modern acoustic datasets of Parkinson’s and control subjects donated by the Department of Neurology in Cerrahpaşa, Istanbul and Departamento de Matemáticas, Universidad de Extremadura, Cáceres, Spain. Among the three proposed detection schemes the Forest by Penalizing Attributes (ForestPA) proved to be a promising Parkinson’s disease detector with a little number of decision trees in the forest to score the highest detection accuracy of 94.12% to 95.00%.

Highlights

  • Parkinson’s Disease (PD) is a neurodegenerative disorder that is mostly reported in older adults

  • The detection accuracy of decision forests has been observed with a change in the number of decision trees for each block of the training-testing split

  • The best training-testing split has been proposed as the Parkinson’s Detection Systems (PDS) with the smallest number of decision tree formation for getting the highest detection accuracy with lowest error rate

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Summary

Introduction

Parkinson’s Disease (PD) is a neurodegenerative disorder that is mostly reported in older adults. It is a late age disease having no visible symptoms at its early stage. This is one of the major problems found in the aged person due to the disorder of neuro-related functions in the brain after Alzheimer [1,2]. In 2015, a study about all-cause mortality revealed more than 177,000 death cases around the globe due to Parkinson’s disease [3]. Parkinson’s disease happened as a result loss of dopaminergic neurons in the substantia nigra as the age progresses. It is essential to detect and diagnose the disease at an early stage

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