Abstract

The neurological ICU (neuro ICU) often suffers from significant limitations due to scarce resource availability for their neurocritical care patients. Neuro ICU patients require frequent neurological evaluations, continuous monitoring of various physiological parameters, frequent imaging, and routine lab testing. This amasses large amounts of data specific to each patient. Neuro ICU teams are often overburdened by the resulting complexity of data for each patient. Machine Learning algorithms (ML), are uniquely capable of interpreting high-dimensional datasets that are too difficult for humans to comprehend. Therefore, the application of ML in the neuro ICU could alleviate the burden of analyzing big datasets for each patient. This review serves to (1) briefly summarize ML and compare the different types of MLs, (2) review recent ML applications to improve neuro ICU management and (3) describe the future implications of ML to neuro ICU management.

Highlights

  • Continuous intracranial pressure (ICP) monitoring is a routine practice in neuro ICUs in attempts to identify increases in ICP associated with decreased cerebral perfusion [26]

  • This study clearly demonstrated that Machine Learning algorithms (ML) can integrate a multitude of multidimensional datasets to improve their predictive performance

  • Koren et al [35] showed that the MLbased software called Neurotrend, had good detection accuracy for certain seizure activity while reducing time for Continuous EEG (cEEG) review; inter-agreement between users was poor for rhythmicperiodic waves and unequivocal EEG patterns

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Summary

Machine Learning in Neurocritical Care

There have been several reviews summarizing the role of ML in neurology/neurosurgery [4,5,6]. This review will [1] briefly summarize ML and compare the different types of ML commonly used in neuro ICU research, [2] review recent ML applications to improve neuro ICU management and [3] describe the future implications of ML to neuro ICU management. STANDARD STATISTICAL APPROACHES “Medicine is a science of uncertainty and an art of probability” - Sir William Osler [7]. The first and most important distinction for clinicians to understand is the difference between ML and standard statistical approaches (SSA), such as linear and logistic regression

Fundamentals of Scientific Inquiry
Complexities of Datasets
Need hypothesis to test Linear data
THE MACHINE LEARNING APPROACH
TYPES OF MACHINE LEARNING
Support Vector Machines
Neural Networks
SEARCH STRATEGY AND SELECTION CRITERIA
EEG and Imaging of Consciousness
MACHINE LEARNING IMPROVES MONITORING WITH INTRACRANIAL PRESSURE
CT Triaging
Biomarkers for Prediction of Delayed Cerebral Ischemia
MACHINE LEARNING TO IMPROVE DETECTION OF SEIZURES IN THE NEURO ICU
MACHINE LEARNING TO BETTER PREDICT HEMORRHAGIC TRANSFORMATION
MACHINE LEARNING TO DETERMINE NEUROLOGICAL RECOVERY AFTER NEURO ICU STAY
MACHINE LEARNING APPLICATIONS IN HYDROCEPHALUS FOR NEONATES
LIMITATIONS
No recesses of the third ventricle were the most important fetal
FUTURE DIRECTIONS AND CONCLUSIONS
Findings
AUTHOR CONTRIBUTIONS
Full Text
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