Macadamia Genus: An Updated Review of Phytochemical Compounds and Pharmacological Activities

Abstract

The Macadamia genus of the Proteaceae family, which can be found mainly in the southern hemisphere, has many benefits in some disease treatments. Phytochemical compounds and pharmacological activities of this genus were comprehensively reviewed in this article. This article was written by collecting and reviewing a minimum of 50 scientific articles in PubMed, Google Scholar, Science Direct, Elsevier, and PubChem that contain the phytochemical compounds and pharmacological activities of the Macadamia genus. The articles were published in the last 15 years, a minimum of 20 articles in the last 2 years, and they also must have a DOI. The phytochemical compounds that comprised of flavonoid, proanthocyanidin, and other polyphenols compounds. These phytochemical compounds can promote a wide range of pharmacological activities such as antioxidant, anti-inflammatory, anti-dyslipidemia, dietary controlled, antimicrobial, chemopreventive, and NAFLD prevention. Nevertheless, many investigations on phytochemical compounds and pharmacological activities only focussed on a few parts of a plant, especially nuts. Therefore, further research is needed to determine the other parts of Macadamia genus plants' potential chemical compounds and pharmacological activities.