Abstract
Preliminary evidence highlighted inherited predisposition to lung cancer (LC) related to certain pathogenic germline variant (PGV) in cancer-predisposing genes. Liquid biopsy is able to identify incidental PGV (iPGV) in patients with non-small cell lung cancer (NSCLC), but so far, the frequency and the clinical/molecular profile of patients with NSCLC and PGV is unknown. Here, we report the iPGV detected in cfDNA and the clinical/molecular profile of carriers with advanced (a) NSCLC.
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