M306 PEANUT INDUCED ANAPHYLAXIS IN AN INFANT ORAL FOOD CHALLENGE REQUIRING TWO DOSES OF EPINEPHRINE

Abstract

In 2015, the LEAP study1 described the benefits and safety of early Introduction of peanut. Subsequently, in 2017, the NIAID published updated guidelines2 outlining an approach to introducing peanut to infants, including a protocol for peanut oral food challenges (POFC). This report describes an episode of anaphylaxis in an infant during a POFC while implementing the NIAID Guidelines. This case raises considerations regarding dosing and emergency preparedness.