Abstract

Haemophilus influenzae is a pleomorphic gram-negative bacteria commonly found within the respiratory tract. Haemophilus influenzae serotype b (Hib) is a typeable (encapsulated) strain known to cause invasive disease. Hib polysaccharide-protein conjugate vaccines stimulate a highly immunogenic T-cell dependent response which has dramatically decreased the incidence of invasive disease. Here we present a case of Hib meningitis resulting in sensorineural hearing loss in an immunized infant, presumed to be secondary to vaccine failure.

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