Abstract
rical tests, as appropriate. All statistical analyses were carried out using SPSS 11.0 (SSPS inc., Chicago, IL, USA) statistical software package. RESULTS: We tested 41 cases (28 with MC and 13 with UC) and 39 controls. Among patients, 4 of them had elastase levels indicative of pancreatic insufficiency (<200 ug); 2 patients with UC and 2 patients with MC. All controls had normal level of elastase-1. Overall, we found significant differences in mean levels of stool elastase between cases and controls. No differences in stool elastase means +/SD were found comparing MC and UC (Mean Elastase +/SD in stool among patients with UC vs MC were 611.86 +/101.91 vs. 726.25+/51.58, respectively, t-test t=-1.117, p=0.271). No significant differences were found regarding to gender in patients and controls. CONCLUSION: Finding pancreatic insufficiency in 10,89% of the included patients suggests association between IBD and PI. Further investigations have to be done to answer which factors are responsible for impaired pancreatic function in IBD.
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