Abstract
was recorded again with the number of polyps detected. Results: A total of 58 patients in each group were included. The number of patients with decrease in spasm score of 0, 1, and 2 between insertion and withdrawal were 6 (11.1%), 46 (85.2%), and 2 (3.7%) in the Hyosine group, and 2 (3.7%), 30 (55.6%), and 22 (40.7%) in the Placebo group, respectively (p<0.001). Overall, no significant differences were observed in the number of polyps detected per patient. However, in subgroup analysis of patients with spasm score≥ 3 during insertion, more polyps per patient were likely to be detected in the Hyoscine group than the Placebo group (1.21±2.23 vs. 0.41±0.91; p=0.060). Conslusions: Our study suggests that hyoscine might increase the detection rate of polyps in patients with moderate to marked degree of colonic spasm during colonoscope insertion. Further large scale studies are needed to validate our observations. Table 1. Spasm score
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