Abstract

Delayed cutaneous reactions occur in up to 24% of patients receiving mogamulizumab for cutaneous T-cell lymphoma (CTCL). This ‘mogamulizumab-associated rash’ is the most common adverse event leading to mogamulizumab discontinuation. Safe and effective methods to reintroduce mogamulizumab would allow continued treatment with this potentially life-saving medication. We present 2 patients with mogamulizumab-associated rash who were able to receive mogamulizumab via outpatient desensitization without rash recurrence.

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