Abstract
Serum sickness, an immune-complex-mediated hypersensitivity reaction, is more common in adults than children. Rituximab has been reported as an agent that can cause serum sickness. This case discusses a pediatric patient who developed rituximab-induced serum sickness in the setting of a positive history of COVID-19 and recently diagnosed neuromyelitis optica, celiac disease, immune thrombocytopenia, and Sjogren’s syndrome.
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