Abstract

In 2005, Prange and colleagues identified a localized variant of acute generalized exanthematous pustulosis (AGEP) they termed ‘acute localized exanthematous pustulosis’ (ALEP). ALEP is characterized by sterile pinhead-sized nonfollicular pustules over an erythematous base typically distributed on the face, neck, or chest. Over 80% of cases are in response to medications, with beta-lactam antibiotics being frequently implicated. We describe a case of facial ALEP that developed three days after initiating amoxicillin-clavulanate therapy.

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