M-N-125 REACTION TIME IN A MONETARY INCENTIVE TASK DOES NOT DIFFER BETWEEN NARCOLEPSY PATIENTS AND HEALTHY CONTROLS

Abstract

of the drugs used for treatment. The Minnesota Multiphasic Personality Inventory (MMPI) is the clinical test used most frequently to identify personality profiles and for diagnosing different psychopathologies. It is composed of multiple scales, including six critical variables with a greater influence in the treatment decision. Materials and Methods: We have performed a comparative and observational study using the latest version of the MMPI-2RF in 10 patients in our sleep laboratory diagnosed with Primary Hypersomnia. The range of age was 18 to 40 years. 7 of them had Narcolepsy, 3 of them with Cataplexy, and 3 had Idiophatic Hypersomnia. None of them had a history of psychiatric or somatic problems. The education level of the patients was at least the high school level. We compared the results with 10 healthy controls with similar demographic characteristics but without sleep disorder. Previous informed consent was obtained from all patients. Results: Preliminary results showed in patients a high level of demoralization, somatization, absence of positive emotions, hopelessness and no motivation for change. Many patients showed a propensity for violence, familial conflicts and impulsivity. None of these characteristics were identified in the control group. We performed a statistical analysis with the data. In a discriminant analysis between the critical variables, we found that a combination of two factors, specifically anxiety (AXY) and defenselessness (HLP), were capable of separating patients from the control subjects. Conclusion: Based on preliminary data we have found a specific psychopathological profile in patients with Primary Hypersomnia but a more detailed and extensive study is needed to provide consistent data. In our experience, we suggest that these patients need specific psychological support.