Abstract

The activity of acid phosphatase in cerebrospinal fluid (CSF) from 7 Huntington's chorea patients tended to he higher than in 7 controls. The activity of arylsulphatase in CSF was the same in the two groups. In the Huntington's group, but not in the control group, the activity of acid phosphatase in CSF was positively correlated with age. No correlation was found between the CSF and serum levels of acid phosphatase and arylsulphatase. The concentrations of tyrosine, tryptophan, homovanillic acid and 5-hydroxyindolylacetic acid in CSF from the Huntington's chorea patients were not significantly different from control values. The concentration of tryptophan, but not of tyrosine, was significantly reduced in plasma from fasted Huntington's chorea patients.

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