Abstract
Changes in the activities of α‐galactosidase, β‐galactosidase and a‐arabinosidase in amniotic fluid cells with time in culture were studied. Marked fluctuations in all three enzymes occurred with passage. In certain cell strains, β‐galactosidase showed a marked rise in activity correlated with passage. The activity of all three enzymes, in amniotic fluid cells at the third passage, was correlated with the total time taken to reach con‐fluency. There was no consistent pattern of enzyme activity associated with the time after subculture. Enzyme levels in cell strains derived from serial samples of amniotic fluid from several women showed large differences in activity unrelated to gestational age.
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