Abstract
Lymphocyte Immunotherapy is Not Necessary for Primary Unexplained Abortions
Highlights
Human conceptus is a semi-allograft and antigenically foreign to the mother, the process of implantation may include mechanisms preventing allograft rejection, once the immunological tolerance is imbalanced, pathological pregnancy, such as spontaneous abortion would occur [1]
Recurrent Pregnancy Loss (RPL) can be classified into primary RPL and secondary RPL [2]
It attributes to the production of Anti-paternal Cytotoxic Antibodies (APCAs) in women with RPL
Summary
Human conceptus is a semi-allograft and antigenically foreign to the mother, the process of implantation may include mechanisms preventing allograft rejection, once the immunological tolerance is imbalanced, pathological pregnancy, such as spontaneous abortion would occur [1]. Lymphocyte Immunotherapy is Not Necessary for Primary Unexplained Abortions *Corresponding author: Wen-Juan Wang, Reproduction Medical Center, Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, 264000, China, Tel: +86-535-6691999-83907; Fax: +86-535-6240341; E-mail: sdwangwj@126.com
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