Abstract
SINCE 1948, when Stewart and Treves reported six cases of lymphangiosarcoma developing in a lymphedematous arm following radical mastectomy,173 cases of this syndrome have been reported in world medical literature. However, many others must have been seen and treated without being reported and probably many more have not been diagnosed. We are now reporting three additional cases in this presentation. The clinical picture of all 76 cases is rather similar (Tables 1 and 2). The patients usually give histories of radical or simple mastectomy complicated by lymphedema of the arm, or long-standing lymphedema due to reasons other than mastectomy. The first sign of new lesions is the appearance of a bluish or reddish-purple nodule in the skin of the arm. As the lesion enlarges, other lesions arise around the original one. To the patients, the first lesion simulates a bruise. Subsequent course of the disease is fast, and
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