Lymph node metastases of the neck in unknown primary tumor: is there a differential imaging diagnosis?

Abstract

In 32 patients suffering from cervical lymph node metastases with an unknown primary tumour the pretherapeutic findings via sonography, CT and MR were compared and the post-therapy findings of tumour aftercare assessed. After an average follow-up period of 38 months the group of branchiogenic cervical cysts had no recurrence. In the group of 18 patients with more than one cervical lymph node metastasis without primary tumour, either the primary tumour or further lymph node metastases became manifest in 11 patients after an average follow-up period of 36 months. Imaging of the number of lymph node metastases and differentiation between malignant degenerated branchiogenic cysts and lymph node metastases without primary tumour is important for prognosis. A combination of findings from sonography, CT and MR enables performance of such differential diagnosis due to morphological aspects and aspects that are conditioned by the contrast medium.