Abstract

Diagnosing Lyme disease involves assessment of the patient’s symptoms and EM rash. When EM rash and recent tick exposure are evident, additional laboratory tests may not be required. However, in cases where there is no EM rash or a clear history of tick exposure, a Lyme disease diagnosis may involve blood antibody tests. Serological testing, such as ELISA and immunoblots, is a common approach, and ELISA is reliable when IgG levels are at or above 200 IU/ml.

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