Abstract

Stage IV acute cutaneous graft-versus-host-disease (GVHD) is nowadays rarely seen due to tissue typing done before transplant. The first line treatment for acute GVHD grade II-IV is systemic corticosteroids. However, although there is no consensus for refractory cases, literature report diverse therapies to be effective. We report the case of a 34 year-old patient with refractory acute cutaneous graft-versus-host-disease stage IV successfully treated with etanercept

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