Abstract
Background and aim: The QGS program used to quantify left ventricular functional parameters from gated myocardial perfusion SPECT imaging (MPI) has been extensively evaluated and compared with other quantitative computer software programs. Little has been done, however, to assess the reproducibility of the QGS algorithm on different processing systems. This study was performed to evaluate results obtained with QGS using two different workstations. Methods: Gated MPIs of 50 patients were analysed. Filtered back-projection (FBP) was performed on 2 systems (Pegasys, Hermes) while iterative reconstruction (IR) was done on one system (Pegasys) and transaxial slices then transferred to Hermes. QGS was used to calculate the left ventricular end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (LVEF) for both reconstruction methods. Results: Mean differences for functional parameters between the systems are given in Table 1. Bland–Altman plots showed definite trends for EDV and ESV using FBP but none for IR. Excellent correlation was obtained for all parameters with both FBP and IR.Table: 1 Results of filtered back-projection and iterative reconstruction for cardiac parametersConclusion: The difference in EDV and ESV for FBP can be ascribed to reconstruction differences (e.g. filters) between the two systems. However, when IR data were analysed on the two systems, no differences in QGS results were observed.
Published Version
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