Abstract
The authors present a case of lupus miliaris disseminatus faciei , a rare skin disease of unknown etiology, which may cause unaesthetic scarring due to its difficult treatment. The histopathological examination of epithelioid granulomas with caseating necrosis, together with the clinical features, are important for diagnosis and early treatment with better results. Despite difficult and unsatisfactory treatment, there are ongoing studies on therapy to improve aesthetic and social impairment. This case report describes an initial misdiagnosis delaying appropriate treatment, [...]
Highlights
Lupus miliaris disseminatus faciei (LMDF) is a rare skin disease of inflammatory character and unknown etiology. It was described by Fox, in 1878, and predominantly affects young adults with brownish-erythematous papule pattern in the central region of the face, eyelids and periocular region, which can be accompanied by facial abnormalities.[1,2,3] The histopathological findings of epithelioid granulomas with caseating necrosis and the clinical presentation are fundamental to make definitive diagnosis..(4) Differential diagnoses include acne, sarcoidosis, facial Afro-Caribbean childhood eruption (FACE), and bacterial and fungal infections.[1,2,3] The difficult and unsatisfactory treatment has been currently studied, aiming to improve aesthetic and social impairment
Histopathologic examination showed granulomas consisting of epithelioid histiocytes, giant cells, lymphocytes and central necrosis in the dermis
In several reports, it was possible to observe improvement and minimal scars associated with early treatment.[1,2,3,4,5]
Summary
Lupus miliaris disseminatus faciei: quando uma rara dermatose acomete a pálpebra. Carolina Ando Matsuno , Tatiana Rizkallah Nahas , Ilana Maeda Yamakami , Nilceo S. Michalany , Celia Simões Cardoso de Oliveira Sathler. How to cite: Matsuno CA, Nahas TR, Yamakami IM, Michalany NS, Sathler CS. Lupus miliaris disseminatus faciei: when a rare skin disease involves the eyelid. Institution: Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil. Conflict of interest: no conflict of interest. Financial support: the authors received no financial support for this work
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