Abstract
Lung-Centered Open Heart Surgery: A Call for a Paradigm Change.
Highlights
Specialty section: This article was submitted to Heart Surgery, a section of the journal Frontiers in Cardiovascular Medicine
“The time has come,” in the famous words of Lewis Carroll, “to talk of many things,” and we would like to talk about many things that lead to severe pulmonary dysfunction after cardiac surgery
The right ventricular performance may be impaired in the early post-bypass period due to cardioplegia-induced edema and swelling, regional tissue electrolyte, metabolic and temperature heterogeneity, and ischemia–reperfusion injury
Summary
Specialty section: This article was submitted to Heart Surgery, a section of the journal Frontiers in Cardiovascular Medicine. Ischemic and atelectatic organ, subjected to oxygen toxicity and ventilator-induced injury during pre-bypass period, is exposed to CPB-induced systemic inflammatory response (SIRS), greatly potentiated by sequestration of activated polymorphonuclear leukocytes in pulmonary capillaries.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
