Abstract
Measurement of lung volumes and certain ventilatory variables during treadmill exercise with a 5-mm expiratory airway obstruction revealed significant changes in residual volume, expiratory reserve volume, and lung clearance index as compared to values obtained without obstruction. These variations in themselves do not explain previously observed large decrements in oxygen utilization with acute airway obstruction. However, the additive effects of decreased alveolar ventilation and alterations in intrapulmonary gas distribution could account for this phenomenon. expiratory airway obstruction; lung volume changes with airway obstruction; decreased oxygen utilization with resistance breathing; treadmill exercise and resistance breathing; ventilatory alterations with obstructed expiration Submitted on April 19, 1963
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