Lung SOL- Cytology and histological correlation in a tertiary care centre

Abstract

Computed Tomography (CT) guided Fine needle aspiration cytology (FNAC) is nowadays considered to be a rapid, safe and accurate diagnostic modality in diagnosis of lung cancer with minimal complication. The purpose of the present study is to find out the correlation between cytology and histopathology and to assess the accuracy of FNAC in evaluation of lung masses. 120 patients were studied for a period of 1 year from January 2013 to December 2013. The cytological features were correlated with histological findings after performing bronchoscopic biopsy or percutaneous core biopsy. Out of the 120 cases in which cytological evaluation was done, biopsy was possible in 103 cases. Of these, 95 cases were adequate for histopathological evaluation and were included in the study. The peak age incidence was found to be 61 to 70 years. Prevalence was more in males (80.84%) compared to females. On cytology, 107 (89.17%) cases were malignant neoplasms and non-neoplastic (inflammatory) lesions were found in 13(10.03%) cases. Most common type of malignancy was squamous cell carcinoma (60.74%) followed by adenocarcinoma (21.49%). Excellent concordance rate of cytology and histology was observed statistically. Diagnostic accuracy of CT guided FNAC was found to be 95%. This study concludes that CT guided FNAC is a safe procedure with high degree of concordance with histological diagnosis and can be used independently in choosing treatment opinion.