Abstract
目的 探讨肺复张与高频振荡通气在早产儿呼吸窘迫综合征(respiratory distress syndrome,RDS)中的疗效。 方法 选取广东省第二人民医院新生儿重症监护室住院的符合纳入标准的RDS早产儿,随机序列法分为肺复张组与高频组,其中肺复张组在常频机械通气的同时行肺复张。记录两组新生儿治疗后6 h的吸入氧浓度(raction of inspired oxygen,FiO2)、平均气道压(mean airway pressure,MAP),计算氧合指数(oxygenation index,OI),并进行比较。对两组的总呼吸支持时间和总吸氧时间进行分析比较。 结果 肺复张组与高频组各10例,两组患儿性别、胎龄、出生体重以及肺复张前FiO2及OI比较差异均无统计学意义(P>0.05)。肺复张组6 h的FiO2及OI均低于高频组[(0.3±0.1)比(0.4±0.1)、(3.2±1.5)比(6.9±2.7)](P<0.05)。与肺复张组比较,高频通气减少总呼吸支持时间及总吸氧时间[(105.2±52.6)h比(185.2±94.7)h、(353.5±199.6)h比(644.1±357.4)h](P<0.05)。 结论 肺复张能较快改善氧合,但高频通气减少呼吸支持时间及氧疗时间。
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