Abstract
Background: The aim of this paper was to evaluate the thoracic manifestations associated with the Connective tissue disorders, with an emphasis on interstitial and airway disease pattern on the High Resolution computed tomography (HRCT) findings. Subjects and Methods: The present study was conducted for a period of one year. A total of 50 patients with various connective tissue disorders having respiratory complaints were evaluated. Results: During the study period 50 patients (80%females and 20%males) underwent evaluation. Cough and dyspnea were the most common presenting symptoms. Variety of thoracic abnormalities weredetected in 67 (95%) cases. Most common abnormality detected on HRCT was interstitial fibrosis/interstitial lung disease present in (60%) cases. Most common parenchymal abnormalities seen were reticulations (61.4%), ground glass opacification (40%), mosaic attenuation (32.8%) and honeycombing (24.3%). Airway abnormalities seen were bronchiectasis (48.5%), emphysema (12.8%), and ground glass nodules (2.8%). Conclusion: Interstitial lung disease is the most common pulmonary manifestation among patients with connective tissue disorders, and early detection and prompt treatment is expected to improve the outcome.
Highlights
Interstitial lung disease (ILD) is a group of diffuse parenchymal lung diseases affecting the pulmonary interstitium.[1]High resolution computed tomography is the most accurate, noninvasive, cross section imaging modality for the diagnosis and follow up monitoring of ILD. [2,3,4]This Study was done to check the basic High Resolution computed tomography (HRCT) patterns associated with Interstitial Lung Disease and correlation of HRCT patterns with clinical data in differential diagnosis of Interstitial Lung Disease. [5,6]
Sample size= 50 Study design= Prospective study Type of study= Single centre Duration of study= 1yr Place of study=PDU Medical college & govt. hospital, Rajkot Consent for participation in study= Yes Patient Selection Inclusion Criteria Patients referred from medicine or skin department of our Radiology department having clinical suspicion of ILD
We showed that pleural effusion was the most frequent finding in patients with Systemic lupus erythematosus (SLE) which is in contrast to Fenlon et al’s findings
Summary
Interstitial lung disease (ILD) is a group of diffuse parenchymal lung diseases affecting the pulmonary interstitium.[1]High resolution computed tomography is the most accurate, noninvasive, cross section imaging modality for the diagnosis and follow up monitoring of ILD. [2,3,4]This Study was done to check the basic HRCT patterns associated with Interstitial Lung Disease and correlation of HRCT patterns with clinical data in differential diagnosis of Interstitial Lung Disease. [5,6]. Interstitial lung disease (ILD) is a group of diffuse parenchymal lung diseases affecting the pulmonary interstitium.[1]. The aim of this paper was to evaluate the thoracic manifestations associated with the Connective tissue disorders, with an emphasis on interstitial and airway disease pattern on the High Resolution computed tomography (HRCT) findings. A total of 50 patients with various connective tissue disorders having respiratory complaints were evaluated. Most common abnormality detected on HRCT was interstitial fibrosis/interstitial lung disease present in (60%) cases. Most common parenchymal abnormalities seen were reticulations (61.4%), ground glass opacification (40%), mosaic attenuation (32.8%) and honeycombing (24.3%). Conclusion: Interstitial lung disease is the most common pulmonary manifestation among patients with connective tissue disorders, and early detection and prompt treatment is expected to improve the outcome
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