Abstract
LETTERS TO THE EDITORLung compliance measurement in miceYuh-Chin Tony HuangYuh-Chin Tony HuangPublished Online:01 Apr 2008https://doi.org/10.1152/ajplung.00052.2008MoreSectionsPDF (28 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations to the editor: I read the article by Martin et al. (1) in the September 2007 issue of AJP-Lung. The authors presented interesting observations of increased lung compliance in TIMP-3 null mice during a septic insult. Lung compliance was measured by the linear regression method, the constant phase model, and indirectly by light microscopy morphometry. However, they failed to provide data on static lung compliance using the pressure-volume curve, the gold standard for measuring lung recoil. It would have been an easy postmortem measurement in an open chest mouse using flexiVent. Without the measurement of true lung recoil property, their results remain uncertain.REFERENCE1 Martin EL, Sheikh TA, Leco KJ, Lewis JF, Veldhuizen RA. Contribution of alveolar macrophages to the response of the TIMP-3 null lung during a septic insult. Am J Physiol Lung Cell Mol Physiol 293: L779–L789, 2007.Link | ISI | Google ScholarAUTHOR NOTESAddress for reprint requests and other correspondence: Y.-C. Tony Huang, Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University Medical Center, Durham, NC 27710 (e-mail: [email protected]) Download PDF Previous Back to Top Next FiguresReferencesRelatedInformation Cited ByCthrc1 lowers pulmonary collagen associated with bleomycin-induced fibrosis and protects lung function14 March 2017 | Physiological Reports, Vol. 5, No. 5Reply to HuangErica L. Martin, and Ruud A. W. Veldhuizen1 April 2008 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 294, No. 4 More from this issue > Volume 294Issue 4April 2008Pages L815-L815 Copyright & PermissionsCopyright © 2008 the American Physiological Societyhttps://doi.org/10.1152/ajplung.00052.2008PubMed18391226History Published online 1 April 2008 Published in print 1 April 2008 Metrics
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: American Journal of Physiology-Lung Cellular and Molecular Physiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
