Lung colloidal adenocarcinoma - A case report and review of relevant documentation

Abstract

According to the histopathological classification of lung tumors of the World Health Organization (WHO) 2015, update 2021, the adenocarcinoma group includes the following subtypes: (1) minimally invasive adenocarcinoma (MIA); (2) Invasive non-mucinous carcinoma (INMA); (3) Invasive mucinous carcinoma (IMA); (4) Colloidal adenocarcinoma (CA); (5) Fetal cancer (FA); (6) Enteric-type adenocarcinoma (EA). In which group colloidal cancer (CA) is said to be very rare, with high malignancy, rapid progression, very difficult to treat. The definitive diagnosis of lung cancer (LC) in general and Adenocarcinoma in particular is still the absolute role of pathology; The problem of subtype LC diagnosis is essential for treatment and prognosis. We present a rare case of CA with a giant mucinous mass in the lower lobe of the right lung, destroying the diaphragm descending to the abdomen, making preoperative diagnosis extremely difficult. The patient underwent surgery to remove the lower lobe of the right lung, and the postoperative specimens were diagnosed with CA; The prognosis after surgery was very conservative. Through the report, we hope that colleagues will have a better diagnostic approach when encountering a similar case.