Abstract

favorable malignant diseases globally. In the Republic of Belarus, it ranks third (8.2%) in the cancer incidence structure and
 first (21.5%) in the cancer mortality structure.
 The object of the study were the lung cancer incidence and
 mortality trends in the Republic of Kazakhstan in 1990-2019.
 Methods: The present study included all patients - residents of Belarus, registered in the national cancer registry from
 1990 to 2019 with a diagnosis of lung cancer (ICD-10 code:
 C33-C34). Demographic variables included gender, age, and
 area of residence (urban or rural). The number of PD cases is
 presented as absolute values and rough intensity indicators
 per 100,000 population. Standardized morbidity and mortality
 rates are calculated using the world standard (World) and are
 indicated per 100,000 population.
 Results: In the study period, the standardized incidence
 rate decreased from 27.5 to 25.6 per 100 000 population
 (– 7.1%, p<0.01). In males, it decreased from 62.1 to 54.6 per 100
 000 males (– 12.1%, p<0.001); in females, it increased from 5.3
 to 6.4 per 100 000 females (+20.7%, p<0.05).
 The standardized lung cancer mortality rate has decreased
 over the study period from 23.0 to 18.3 per 100 000 population
 (– 20.4%, p<0.001). In males, it went down from 53.6 to 40.7 (–
 24.1%, p<0.001), and in women it changed slightly from 3.6 to
 3.7 (+2.8%, p>0.05) per 100 000 of the relevant sex. The average annual increase in standardized mortality decreased eight
 times faster than the growth in standardized incidence.
 Conclusion: In the Republic of Belarus, lung cancer incidence is increasing in males and decreasing in females. At that,
 lung cancer mortality is decreasing. Quality specialized cancer
 care creates conditions for quicker negative growth of lung cancer standardized mortality vs. incidence

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