Abstract

SummaryLung and colon cancers are dangerous diseases that can grow in organs and create a negative impact on human life in certain cases. The histological detection of such malignancies is one of the most critical parts of optimal treatment. As a result, the important objective of this article is to create an effective computerized diagnosis system for identifying adenocarcinomas of the colon as well as, adenocarcinomas and squamous cell carcinomas of the lungs using digital histopathology images and the combination of deep and machine learning techniques. For this, an effective optimized hybrid deep and machine learning framework is developed. This framework consists of two stages. In the first stage, the features of lung and colon images are extracted by principle component analysis network. Then the effective classification is conducted based on extreme learning machine (ELM) with the rider optimization algorithm which classifies lung and colon cancer into five types. The empirical investigation shows that the classification results on the benchmark LC25000 dataset have improved significantly. The use of this model will aid medical professionals in the development of an automatic and reliable system for detecting various forms of lung and colon cancers.

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