Abstract
This article reviews some of the important aspects of lumpy skin disease (LSD) that may impact on its successful control. A resurgence of the disease in the last decade has highlighted some constraints of the Neethling strain vaccine, but there is no evidence of vaccine breakdowns owing to the presence of heterologous field strains. More research is needed on epidemiology and transmission of LSD in South Africa to formulate control measures.
Highlights
In 1929 a new disease of cattle was reported from Zambia ( Northern Rhodesia)[18] that manifested itself by the appearance of skin nodules
Veterinary researchers identified the aetiological agent as a poxvirus and a vaccine was developed by attenuation of a field isolate, which helped to control further outbreaks[25]
Speculation that the severity of the disease is related to different strains of lumpy skin disease virus (LSDV) has been discounted by researchers, who suggest that the route of vector feeding is a more likely determinant, since experimental intravenous infection causes a higher percentage of generalised infections[8]
Summary
In 1929 a new disease of cattle was reported from Zambia ( Northern Rhodesia)[18] that manifested itself by the appearance of skin nodules. Allerton virus was found to be widespread in cattle throughout South Africa and its clinical signs were often confused with those of true LSD as described by Thomas and Mare in 194522. A similar comparative study of LSDV (SA-Neethling) field isolates collected between 1945 and 1959 with the South African vaccine strain supported their results[24].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the South African Veterinary Association
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
