Luminescence Sensing Method for Degradation Analysis of Bioactive Glass Fibers.

Agata Baranowska,Krzysztof J Kurzydłowski,Marcin Kochanowicz,Piotr Miluski,Magdalena Leśniak,Dominik Dorosz,Izabela Zgłobicka,Jacek M Żmojda,Aleksandra Wajda

doi:10.3390/s21062054

Agata Baranowska, Krzysztof J Kurzydłowski + Show 7 more

Open Access

https://doi.org/10.3390/s21062054

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Abstract

The effects of Sm3+ content on the optical properties and bioactivity of 13-93 bioactive glass were presented. Sm3+ doped glass fibers drawn from bioactive glass were analyzed in simulated body fluid (SBF) for the determination of ion release. Optical analysis of the Sm3+ ions in bioactive glass fibers was used for degradation monitoring. While the fibers were immersed in SBF solution, changes in their luminescence spectra under 405 nm laser excitation were measured continuously for 48 h. The morphology of the fibers after the immersion process was determined by SEM/EDS. It was shown that the proposed approach to the analysis of changes in Sm3+ ion luminescence is a sensitive method for the monitoring of degradation processes and the formation of hydroxycarbonate-apatite (HCA) layers on glass fiber surfaces. SEM/EDS measurements showed a significant deterioration on the surface of the fibers and the formation of HCA on 13-93_02Sm bioactive glass. The optical analysis of the time constant indicated that bioactive glass fibers doped with 2 %mol Sm3+ degrade at a rate almost five times slower than 13-93_02Sm.

Highlights

Larry Hench developed the first bioactive glass composition (45S5) in 1969 [1]
The optical and biological properties of 13-93 glass fibers doped with various concentrations (0.2 and 2 %mol) of samarium ions were characterized
The results revealed that luminescent properties can be useful to monitor the degradation process of bioactive glass fiber with in vitro measurements

Summary

Introduction

Larry Hench developed the first bioactive glass composition (45S5) in 1969 [1]. Its impressive biological properties have found wide application in the field of medicine, requiring the development of fibers with different glass forms. There is incessant demand for bioactive glass fibers with biomedical applications [3]. Due to their excellent mechanical and biological properties, they are sought as reinforcing elements in composites [4,5]. From a clinical perspective, the fibers, due to their geometry and the possibility of controlled length and thickness, are an attractive material for the support of nerve regeneration [6]

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