Abstract
Abstract The multifunctional Fe3O4/Au/Eu [1-(2-Naphthoyl)-3,3,3-trifluoroacetone]3 nanocomposite (NC) composed of luminescent europium(III) complex with 1-(2-naphthoyl)-3,3,3- trifluoroacetone (NTA) ligands (Eu(NTA)3), superparamagnetic Fe3O4 and plasmonic gold nanoparticles (FAEu(NTA)3) is developed for theranostic application. The FAEu(NTA)3 NC has been functionalized by 3-(mercaptopropyl)trimethoxysilane/3-(triethoxysilyl)-propylamine (MCPMS/TESPA) and conjugated with IgG antibody. This study was focused on luminescent properties and evaluation of the temperature dependent luminescence of FAEu(NTA)3 NC. The in vitro fluorescent imaging test of the prostate cancer PC3 cells incubated with FAEu(NTA)3 NC has been also presented.
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