Abstract

Purpose: Narafilcon A (daily disposable, silicone hydrogel) has been previously shown to be equivalent to no lens wear after one year in several key areas of physiology including corneal staining and papillary changes (Morgan et al., CLAE 2013). The material contains a high molecular weight wetting agent, polyvinylpyrrolidone (PVP), which has individual repeating units similar in function to ocular mucins in providing a lubricious (low friction) surface. It is hypothesized this lubricious interface helps to minimize the interaction between the contact lens (CL) and the eye. The purpose of this study was to evaluate the coefficient of friction (CoF) of PVP, narafilcon A and human corneal tissue in vitro to help elucidate the previously published clinical performance findings.

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