<title>Thymic serum activity and laser-correlation spectra of patients with lower jaw fracture before and after intravenous laser irradiation</title>

Abstract

The problem of jaw-face traumatism is actual in surgical stomatology and fracture of lower jaw make up about 90% from all types of traumas. Number of approaches that include non- specific stimulation of immune system by intravenous laser irradiation were used to raise efficacy of treatment of above indicated fractures. But the application of laser beam irradiation must be controlled by independent biochemical and immunological methods. In particular it is considered the necessity of preliminary analysis of immune system state to determine dose loading of this factor. In dependence on immune system activity the laser beams can promote treatment or reduction of its efficiency. In this report the experimental data about necessity of such control in case of usage of laser beam irradiation are demonstrated. The levels of thymic serum activity (TSA), inhibitors TSA (ITSA) and sub-fractional distribution of substances in blood serum were analyzed in two groups of patients with the fracture of lower jaw: (1) with ordinary treatment and (2) with additional inclusion of number of procedures of laser irradiation. The total quantity of investigated patients was 16. It was shown that: (1) at the irradiation of patients with the normal original TSA level in blood plasma: (a) TSA decreased; (b) ITSA appeared; (c) laser-correlation spectrums changed that indicated about increase of level of substance with less translation mobility and (d) the overall term of recovery increased for 1 day; (2) when the original TSA was lower, above mentioned parameters changed into opposite direction as it is indicated in point 1. So, low intensive laser radiation can have both positive and negative effect in dependent on original organism state.