&lt;b&gt;Inflammatory response after session of resistance exercises in untrained volunteers

Andre De Oliveira Teixeira,Maicon Borjes De Moraes,Felipe Da Silva Paulitsch,Carlos Eduardo Da Rosa,Marina De Moura Umpierre,Luis Ulisses Signori

doi:10.4025/actascihealthsci.v37i1.24149

Abstract

The present study aimed to investigate the interaction between the blood cells, inflammatory markers, oxidative stress parameters and delayed onset muscle soreness (DOMS) after a session of resistance exercise (SRE). The sample consisted of sixteen untrained men (26.4±5 years; 25.9±3 kg m -2 ). The SRE was composed of 4 sets of 10 repetitions maximum (extensor bench, squat and leg press) for each exercise. Complete blood cell count, C-reactive protein (CRP), creatine kinase (CK), lipid peroxidation and antioxidant capacity against peroxyl radicals were previously evaluated (baseline), and at 0, 30 and 120 min. after the SRE. DOMS was assessed 24 hours after the exercises. Immediately after the SRE, an increase of blood cell number was observed; returning to baseline after 30 min. However, after 120 min., neutrophils showed higher values than the baseline and 30 min. assessments. CK and CRP increased progressively throughout the experiment. LPO increased immediately and 120 min. after the SRE. Untrained volunteers presented an apparent biphasic inflammatory response after an acute SRE and the changes in oxidative stress, inflammatory markers and leukocytosis were best evidenced two hours after exercise.

Highlights

The regular practice of physical exercises promotes anti-inflammatory effects, which reduces the mortality from all causes, especially by chronic inflammatory diseases, such as cardiovascular diseases and type 2 diabetes (PETERSEN; PEDERSEN, 2005)
Our results are in accordance to previous studies (PEAKE et al, 2005; MENDHAM et al, 2011), which showed that leukocytosis occurs due to neutrophilia after the session of resistance exercise (SRE)
We emphasize that the period of 2 hours after SRE coincided with the peak concentration of inflammatory markers and the resulting neutrophilia (VELLA et al, 2012), once the hemoconcentration has already been reverted (AHMADIZAD; EL-SAYED, 2005)

Summary

Introduction

The regular practice of physical exercises promotes anti-inflammatory effects, which reduces the mortality from all causes, especially by chronic inflammatory diseases, such as cardiovascular diseases and type 2 diabetes (PETERSEN; PEDERSEN, 2005). 31-39, Jan.-June, 2015 load, volume, time interval between series and exercises, frequency of the sessions, exercise modes, repetition rate and the sequence of exercises, exert influence over the inflammatory response (SIMÃO et al, 2012). The variables of the training program and/or exercise session, such as Maringá, v. During these exercises, reactive oxygen species (ROS) are formed and, when its production exceeds the antioxidant enzymatic capacity (Superoxide dismutase, Catalase and Glutathione peroxidase) and non-enzymatic capacity (Vitamins A, C, E and uric acid) results in oxidation of cell constituents (FINAUD et al, 2006; RIETJENS et al, 2007)

Objectives

Methods

Results

Discussion

Conclusion