Abstract
Leukotriene B4 (LTB4) is a potent lipid mediator of many inflammatory processes (1,2). In addition, elevated tissue levels of LTB4 have been reported in inflammatory diseases such as psoriasis (3) and inflammatory bowel disease (4). For these reasons, LTB4 antagonists have been developed for the treatment of several inflammatory diseases with the aim of inhibiting LTB4 receptor-mediated neutrophil functions (5–7).
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