Ülseratif kolit olgularında standart konvansiyonel endoskopi mi, dar bant yöntemi ile yapılan endoskopi mi şiddet belirlemede etkindir?

Abstract

Background and Aims: In this study, we aimed to show the differences in determining endoscopic severity in ulcerative colitis between standard white light endoscopy and narrow band imaging by comparing results with the histopathological examination. Materials and Methods: A total of 30 (16 female, 14 male) ulcerative colitis subjects were recruited prospectively. Colonoscopy and biopsy were applied in all subjects. Results: Narrow band imaging was more sensitive than standard white light endoscopy in distinguishing normal endoscopic findings (p=0.0015). Evaluation of the disappearance of vascular pattern was more sensitive with narrow band imaging than with standard white endoscopy (p=0.04). The patients evaluated as normal with standard endoscopy but as not normal with histopathological diagnosis had histopathologically mild to moderate inflammation. Mild to moderate inflammation was more prevalent in histopathological findings than in standard white endoscopy (p=0.015). Conclusions: Narrow band imaging was more sensitive for evaluating the disappearance of vascular pattern than standard endoscopy evaluation in patients with low disease activity. We think this is a precursor study for multi-center studies regarding detection of malignancy in ulcerative colitis with long-term disease.