Abstract
The alterations of cytokines (TNF, PGE2), plasma lipopolysaccharide andtheir prognostic influences in 58 patients with intra-abdominal infection were observed with enzyme linked immunosorbent assay (ELISA) and radioimmunoassay (RIA). The result revealed earlier improvement of abnormal values of parameters, faster reduction of the level of and detectable rate of serum tumor necrosis factor, higher endotoxin detoxication rate and lower morbidity in the treated group than in the control. The theoretical basis of pharmacological effect and possible mechanism were explored.
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