Abstract
A simple and green synthetic method for preparation of functionalized indol-3-yl pyran derivatives was developed. The reactions were carried out by one-pot three-component synthesis of 3-cyanoacetyl indoles, malononitrile/cyanoacetate and various aldehydes/isatins/acenaphthenequinone in the presence of catalytic amount of l-proline. The advantages of this method included straightforward processing, excellent yields, broad substrate scope and environmental friendliness.
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