Abstract
( R)-Glycerol-monolinoleate 4 and ( R)-glycerol-monostearate 5 were isolated from the ethyl acetate extracts of Saururus chinensis roots and ( R)- or ( S)-fatty acid glycerols 4 and 5 were synthesized for confirming their structures and evaluating their inhibitory activities against Lp-PLA 2. The ( R)- 4 and ( S)- 4 exhibited Lp-PLA 2 inhibitory activities with IC 50 values of 45.0 and 52.0 μM, respectively.
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