Abstract
Introduction: Low birth weight (LBW) is one of the main risk factors for neonatal morbidity and mortality. Anemia in developing countries is still quite high compared to developed countries. Low hemoglobin levels in pregnancy can affect the birth of low birth weight babies.Methods: This study used a systematic review method. Studies published between 2015 and 2019. Search for articles was reviewed systematically through Scopus, ScienceDirect, Cochrane, and PubMed databases. The final results obtained 10 articles following the inclusion and exclusion criteria. Calculation result using Meta-Analysis with help of Comprehensive Meta-Analysis (CMA) software.Results: Compare the odds ratio and confidence interval of hemoglobin levels compared to low birth weight events. The results obtained OR 1.449 (95% CI 0.964 – 2.177) and p-Value 0.074 so that there is no relationship of hemoglobin levels in pregnant women ≤ 11gr / dL with the incidence of low birth weight babies. In the heterogeneity test results, I-Squared results obtained by 79.191%, which indicates the value of I-squared heterogeneity> 50% so that the sample used is heterogeneous. Maternal age less than 20 years or more than 35 years, number of parity, pregnancy spacing, and number of problems in the assessment of pregnancy and previous labor.Conclusion: There is no correlation between low maternal hemoglobin levels with the incidence of low birth weight because there are other factors that can affect outcomes such as different respondent characteristics, number of samples, different research countries, different trimester of pregnancy and other factors that can cause research bias.
Highlights
Low birth weight (LBW) is one of the main risk factors for neonatal morbidity and mortality
Compare the odds ratio and confidence interval of hemoglobin levels compared to low birth weight events
The results obtained Odds ratio (OR) 1.449 and p-Value 0.074 so that there is no relationship of hemoglobin levels in pregnant women ≤ 11gr / dL with the incidence of low birth weight babies
Summary
Low birth weight (LBW) is one of the main risk factors for neonatal morbidity and mortality. Low hemoglobin levels in pregnancy can affect the birth of low birth weight babies. Low birth weight are one of the main risk factors for neonatal death. Some of the factors causing low birth weight babies are maternal factors (maternal age, gestational distance, parity, hemoglobin levels, obstetric and nutritional history), placental factors, environmental factors, mother's educational status and socio-economic status. Low hemoglobin levels in pregnant women can cause anemia. Anemia in pregnancy will interfere with oxygenation and the supply of nutrients from the mother to the fetus. The fetus will experience weight gain problems, causing LBW. One of the causes of anemia in pregnant women is a lack of iron intake during pregnancy (Novianti and Aisyah, 2018)
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