Abstract

It has been suggested that lower urinary tract symptoms-benign prostatic hyperplasia (LUTS-BPH) may be a risk factor for inguinal hernia (IH). The aim of this study was to examine the emergence of a subsequent IH diagnosis in men with and without LUTS-BPH. From a database derived from the National Health Insurance Program covering 99% of the population in Taiwan, 22,310 men with LUTS-BPH and 22,310 matched men without LUTS-BPH were identified and followed for IH from 1997 to 2013. Both IH and LUTS-BPH were defined by the ninth revision of the International Classification of Diseases code (ICD9). Subjects younger than 20 years of age and with IH diagnosed before the index date were excluded. We used Cox proportional hazards regression models to estimate hazard ratios (HRs) for subsequent IH, controlling for potential confounders. Men with and without LUTS-BPH had similar age and comorbidity distributions. During the 10 years of follow-up, 1,303 (5.84%) men with LUTS-BPH and 735 (2.53%) men without LUTS-BPH developed IH. The mean time to IH was 4.02 years and 4.44 years, respectively. After adjusting for age and comorbidities, LUTS-BPH was associated with a two-fold increased risk of IH (HR:2.25, 95% CI = 2.04-2.49). This nation-wide population-based cohort study showed that LUTS-BPH increased the risk of subsequent IH in a Taiwanese Population.

Highlights

  • Introduction & objectivesIt has been suggested that lower urinary tract symptoms—benign prostatic hyperplasia (LUTS-Benign prostatic hyperplasia (BPH)) may be a risk factor for inguinal hernia (IH)

  • After adjusting for age and comorbidities, LUTS-BPH was associated with a two-fold increased risk of IH (HR:2.25, 95% confidence interval (CI) = 2.04–2.49)

  • The data underlying the results presented in the study are available from he Longitudinal Health Insurance Database 2005 (LHID 2005), which was released by Taiwan National Health Insurance (NHI) for research purposes

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Summary

Introduction

Introduction & objectivesIt has been suggested that lower urinary tract symptoms—benign prostatic hyperplasia (LUTS-BPH) may be a risk factor for inguinal hernia (IH). The most terrible event is that intestines are trapped and pinched in the groin or scrotum and cannot be moved back into the abdomen, leading to an incarcerated or even strangulated inguinal hernia. This usually produces severe pain and tenderness of the area and the strangulation of intestines, where the blood supply to part of the intestine is blocked, possibly resulting in bowel perforation [6] or gangrene [7]. It is life-threatening and needs emergent surgery [8]

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