Abstract
Background Myocardial infarction (MI) leads to heart failure in a substantial number of patients. Investigation of perfusion in the infarct-adjacent segments can offer better insights into left ventricular remodeling. It is the aim of this study to compare myocardial blood flow (MBF) with cardiac magnetic resonance (CMR) in the infarct borderzones (BZ) and the remote myocardium (RM) in a large patient population in the acute phase of MI.
Highlights
Myocardial infarction (MI) leads to heart failure in a substantial number of patients
Investigation of perfusion in the infarct-adjacent segments can offer better insights into left ventricular remodeling. It is the aim of this study to compare myocardial blood flow (MBF) with cardiac magnetic resonance (CMR) in the infarct borderzones (BZ) and the remote myocardium (RM) in a large patient population in the acute phase of MI
MBF was quantified using Fermi deconvolution with a dual bolus analysis technique (equal volumes of 0.0027 mmol/kg followed by 0.05 mmol/kg after a 20-s pause of contrast agent (Dotarem, Gd-DOTA, Guerbet, France)) in basal and midventricular short axis perfusion slices
Summary
Myocardial infarction (MI) leads to heart failure in a substantial number of patients. Investigation of perfusion in the infarct-adjacent segments can offer better insights into left ventricular remodeling. It is the aim of this study to compare myocardial blood flow (MBF) with cardiac magnetic resonance (CMR) in the infarct borderzones (BZ) and the remote myocardium (RM) in a large patient population in the acute phase of MI
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