LOWER LIP SQUAMOUS CELL CARCINOMA IN A RENAL TRANSPLANT PATIENT: A CASE REPORT

Abstract

Immunosuppressive therapy has as side effects the emergence of conditions and pathologies often with oral manifestations. We report a case of lower lip squamous cell carcinoma (SCC) in a renal transplant patient. A 60-year-old male patient, a farmer, attended the oral medicine service complaining of a mouth sore. In anamnesis, the patient reported being an alcoholic, receiving a renal transplant 15 years ago, and using immunosuppressive drugs. The intraoral examination revealed an ulcerated nodular lesion with hardened and raised edges, sessile and asymptomatic, rapidly growing and located on the lower lip. With the clinical diagnosis of SCC, an incisional biopsy was performed. Microscopic examination revealed malignant neoplasm epithelial cells exhibiting pleomorphism and cellular atypia invading the lamina propria of connective tissue, thus, the clinical diagnosis was confirmed. The patient was referred to oncology therapy where surgical excision was performed with safety margin. The patient is under follow-up with no signs of recurrence.