Abstract

BackgroundMarjolin’s ulcer (MU) of lower extremities usually presents with scar contracture and functional disability. They often follow an aggressive course and poor outcome, and require early radical removal. Split-thickness skin grafts, local flaps, or amputation are commonly practiced surgical options for MU. Though free flaps are gaining popularity for various oncoplastic reconstruction, they are not frequently used for MU. A free anterolateral thigh (ALT) flap may have a beneficial role as it provides simultaneous coverage for a large defect after radical tumor and scar excision.MethodsBetween January 2015 and December 2018, 11 patients with lower limb MU reconstructed with free ALT flap were reviewed retrospectively for the surgical procedure, recurrences, and functional outcomes.ResultsMean dimensions of the defect and flaps were 8 cm × 6 cm and 18.91 cm × 11 cm, respectively, and total flap coverage was obtained in nine cases. Marginal flap loss was noted in one and residual contracture in two cases. Functional improvement of the limb was achieved in all cases. Recurrence or disease-related mortality was not seen in any patient after a mean follow-up of 35.82 months.ConclusionsFree ALT flap reconstruction of MU of extremity facilitates most radical tumor and scar-contracture removal and thus reduces the chances of re-ulceration. It facilitates local radiotherapy protocol with the provision of immediate durable coverage. Thus, it has a beneficial role other than a secondary reconstructive procedure. Moreover, an added benefit may be obtained with a “flow-through’ flap” to avoid amputation and improve functional outcomes.

Highlights

  • Marjolin’s ulcer (MU) is an infrequently encountered malignancy, occurring in a previous scar and commonly seen in the lower extremity

  • A free anterolateral thigh (ALT) flap may have a beneficial role as it provides simultaneous coverage for a large defect after radical tumor and scar excision

  • MUs usually present with squamous cell carcinoma (SCC) in the milieu of a scar and deep-seated contracture, restriction of major joint movement, and functional disability

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Summary

Introduction

Marjolin’s ulcer (MU) is an infrequently encountered malignancy, occurring in a previous scar and commonly seen in the lower extremity. MUs usually present with squamous cell carcinoma (SCC) in the milieu of a scar and deep-seated contracture, restriction of major joint movement, and functional disability. Wide local excision (WLE) and resurfacing with split-thickness skin graft (STSG), local flaps, or amputation are commonly practiced for the surgical management of extremity MU. For extremity MU, plane and margin of resection are often not very evident due to the presence of concomitant deep-seated scar, contracture, and three-dimensional tissue involvement. Simultaneous contracture release and complete removal of the potential scar necessitates a greater amount of tissue to resurface the defect. Marjolin’s ulcer (MU) of lower extremities usually presents with scar contracture and functional disability. They often follow an aggressive course and poor outcome, and require early radical removal. A free anterolateral thigh (ALT) flap may have a beneficial role as it provides simultaneous coverage for a large defect after radical tumor and scar excision

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