Abstract

Loose anagen hair syndrome (LAHS) is a sporadic or autosomal dominant hair disorder which typically affects girls aged 2-6 years.1 It is characterised by increased hair shedding, non-scarring alopecia, inability to grow long hair, dull and lustreless hair. Premature and defective keratinisation of the inner root sheath (IRS), and impaired anchorage of anagen hairs underlie the pathogenesis.1 A favourable response has been demonstrated in three patients with LAHS treated with topical minoxidil.1-3 Low-dose oral minoxidil (LDOM) has been shown to be effective in adult androgenetic alopecia, alopecia areata and telogen effluvium.4 Herein we describe the efficacy and safety of LDOM in LAHS.

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