Abstract

Low-dose antibiotics: current status and outlook for the future.

Highlights

  • Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals

  • The host modulatory aspects of macrolides, tetracyclines, and betalactams are reviewed by Aminov (2013a) underscoring how, for example, macrolides such as azithromycin are routinely used for immunomodulation in patients with chronic pulmonary disease rather than for an antimicrobial effect

  • Azithromycin is used as a tool by Imperi et al to detail how non-conventional thinking about regulating virulence factors or modifying host inflammatory cascades are useful to combating major pathogens such as Pseudomonas aeruginosa (Imperi et al, 2014)

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Summary

Introduction

Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals. The host modulatory aspects of macrolides, tetracyclines, and betalactams are reviewed by Aminov (2013a) underscoring how, for example, macrolides such as azithromycin are routinely used for immunomodulation in patients with chronic pulmonary disease rather than for an antimicrobial effect.

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