Abstract

South Asians (SA) and African-Caribbean (AfC) people are prominent minorities in Britain and North America. SA have a higher incidence and earlier onset of coronary heart disease (CHD) while AfC have lower rates of CHD despite higher blood pressures, stroke incidence and probably heart failure. Traditional risk factors only partially account for these differences [1,2]. Vitamin-D deficiency is more common among AfC and SA compared to Europeans, probably due to melanised skin [3]. Mounting evidence on the relationship between vitamin-D deficiency and adverse cardiovascular outcomes [4] raises the question whether ethnic differences in outcomes may be explained by vitamin-D status.

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