Abstract

Low-temperature plasma is a partially ionized gas obtained at atmospheric pressure and having a macroscopic temperature close to the ambient temperature. The composition of the torch of low-temperature plasma includes charged particles, neutral active particles, including free radicals and particles in metastable states, as well as ultraviolet radiation. The biological effects of plasma are associated with the synergistic effect of the listed factors, each of which has a subliminal concentration that does not cause changes in the biological object. Intensive research on the use of low-temperature plasma in medicine began about 10 years ago, although some pioneering work appeared much earlier, mainly in Russia. Since the mid-2000s. in the world began to actively develop sources of gas plasma, in which the temperature of the plasma torch is reduced to the temperature of the human body. The use of such structures makes it possible to subject the treated surface to direct plasma action and to use the entire spectrum of active plasma components, including photons, electrons, ions, free radicals, and molecules in an excited state. Low-temperature plasma has a number of fundamental advantages, which include high non-specific bactericidal activity, low probability of occurrence of stable forms, the absence of ionizing radiation and highly toxic substances. The described advantages together with a comfortable temperature, relative simplicity and low cost methods, the lack of specific requirements for the treated surface make low-temperature plasma a promising method for the treatment of various pathological conditions.

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